{"id":2558,"date":"2025-10-27T08:35:20","date_gmt":"2025-10-27T07:35:20","guid":{"rendered":"https:\/\/www.oldpharma.it\/%e9%98%bf%e6%9f%8f%e8%a5%bf%e6%99%ae%ef%bc%9a%e5%bd%bb%e5%ba%95%e6%94%b9%e5%8f%98%e8%a7%86%e7%bd%91%e8%86%9c%e7%96%be%e7%97%85%e6%b2%bb%e7%96%97%e7%9a%84%e5%88%9b%e6%96%b0%e8%8d%af%e7%89%a9\/"},"modified":"2025-11-07T11:13:26","modified_gmt":"2025-11-07T10:13:26","slug":"cn-aflibercept-the-innovation-that-has-revolutionized-retinal-disease-therapy","status":"publish","type":"post","link":"https:\/\/www.oldpharma.it\/zh-hant\/cn-aflibercept-the-innovation-that-has-revolutionized-retinal-disease-therapy\/","title":{"rendered":"\u963f\u67cf\u897f\u666e\uff1a\u5f7b\u5e95\u6539\u53d8\u89c6\u7f51\u819c\u75be\u75c5\u6cbb\u7597\u7684\u521b\u65b0\u836f\u7269"},"content":{"rendered":"
\n
\"阿柏西普\"<\/figure>\n<\/div>\n

\u8fd1\u5e74\u6765\uff0c\u89c6\u7f51\u819c\u75be\u75c5\u7684\u6cbb\u7597\u53d6\u5f97\u4e86\u663e\u8457\u8fdb\u5c55\u3002\u8fc7\u53bb\u88ab\u8ba4\u4e3a\u4e0d\u53ef\u9006\u8f6c\u7684\u89c6\u529b\u635f\u4f24\uff0c\u5982\u4eca\u53ef\u4ee5\u901a\u8fc7\u6709\u6548\u4e14\u6301\u4e45\u7684\u6cbb\u7597\u5f97\u5230\u63a7\u5236\u3002\u5728\u8fd9\u4e00\u533b\u5b66\u9769\u547d\u7684\u6838\u5fc3\uff0c**\u963f\u67cf\u897f\u666e\uff08Aflibercept\uff09**\u51ed\u501f\u5176\u521b\u65b0\u7684\u4f5c\u7528\u673a\u5236\uff0c\u6210\u4e3a\u91cd\u65b0\u5b9a\u4e49\u773c\u79d1\u6cbb\u7597\u6807\u51c6\u7684\u751f\u7269\u6280\u672f\u836f\u7269\u4e4b\u4e00\u3002<\/p>\n\n

\n\n

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VEGF <\/strong>\u5728<\/strong>\u89c6\u529b\u4e27\u5931\u4e2d\u7684\u4f5c\u7528<\/strong><\/h3>\n\n

\u8bb8\u591a\u6162\u6027\u773c\u5e95\u75be\u75c5\uff0c\u5982\u6e7f\u6027\u8001\u5e74\u9ec4\u6591<\/strong>\u53d8\u6027\uff08nAMD<\/strong>\uff09\u548c\u7cd6\u5c3f\u75c5\u6027\u9ec4\u6591\u6c34<\/strong>\u80bf\uff08DME<\/strong>\uff09<\/strong>\uff0c\u90fd\u4e0e**\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50\uff08VEGF\uff09**\u7684\u8fc7\u5ea6\u8868\u8fbe\u6709\u5173\u3002VEGF \u80fd\u4fc3\u8fdb\u89c6\u7f51\u819c\u4e2d\u65b0\u751f\u8840\u7ba1\u7684\u5f62\u6210\uff0c\u4f46\u8fd9\u4e9b\u8840\u7ba1\u901a\u5e38\u7ed3\u6784\u8106\u5f31\u3001\u901a\u900f\u6027\u9ad8\uff0c\u5bb9\u6613\u5bfc\u81f4\u6db2\u4f53\u6e17\u6f0f\u3001\u89c6\u7f51\u819c\u6c34\u80bf\u4ee5\u53ca\u611f\u5149\u7ec6\u80de\u7684\u4e0d\u53ef\u9006\u635f\u4f24\u3002<\/p>\n\n

\u963f\u67cf\u897f\u666e\u7684\u4f5c\u7528\u673a\u5236<\/strong><\/h3>\n\n

\u963f\u67cf\u897f\u666e\u662f\u4e00\u79cd\u878d\u5408\u86cb\u767d\uff0c\u80fd\u4ee5\u9ad8\u4eb2\u548c\u529b\u4e0e VEGF \u7ed3\u5408\uff0c\u4ece\u800c\u963b\u6b62\u5176\u4e0e\u7ec6\u80de\u53d7\u4f53\u7ed3\u5408\u3002\u4f5c\u4e3a\u4e00\u79cd**\u201c\u8bf1\u9975\u53d7\u4f53\u201d\uff0c\u5b83\u80fd<\/strong>\u591f\u6291\u5236\u5f02\u5e38\u8840\u7ba1\u7684\u751f<\/strong>\u957f\u5e76\u63a7\u5236\u89c6\u7f51\u819c\u5185\u6db2\u4f53\u7684\u79ef\u805a\u3002 \n<\/strong>\u6700<\/strong>\u7ec8\u7ed3\u679c\u662f<\/strong>\u6539\u5584\u6216\u7a33\u5b9a\u89c6\u529b**\uff0c\u663e\u8457\u964d\u4f4e\u75be\u75c5\u8fdb\u5c55\u7684\u98ce\u9669\u3002<\/p>\n\n

\n\n

\u7ed9\u836f\u65b9\u5f0f\u4e0e\u4e34\u5e8a\u4f18\u52bf<\/strong><\/h2>\n\n

\u963f\u67cf\u897f\u666e\u901a\u8fc7\u73bb\u7483\u4f53\u8154\u5185\u6ce8\u5c04<\/strong>\u7684\u65b9\u5f0f\u7ed9\u836f\uff0c\u8fd9\u662f\u4e00\u79cd\u7b80\u4fbf\u4e14\u5b89\u5168\u7684\u95e8\u8bca\u64cd\u4f5c\uff0c\u53ef\u5c06\u836f\u7269\u76f4\u63a5\u6ce8\u5165\u773c\u5185\u4ee5\u6700\u5927\u5316\u7597\u6548\u3002\u8be5\u6cbb\u7597\u7684\u4e00\u5927\u4f18\u52bf\u662f\u53ef\u5728\u66f4<\/strong>\u957f\u7684\u7ed9\u836f\u95f4\u9694\u5185\u7ef4\u6301\u7a33\u5b9a\u7684\u89c6\u89c9\u529f\u80fd<\/strong>\uff0c\u63d0\u9ad8\u60a3\u8005\u7684\u4f9d\u4ece\u6027\u548c\u751f\u6d3b\u8d28\u91cf\u3002<\/p>\n\n

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\n\n

\u76d1\u7ba1\u6846\u67b6\uff1a\u786e\u4fdd\u53ef\u53ca\u6027\u4e0e\u5b89\u5168\u6027<\/strong><\/h2>\n\n

\u5728\u610f\u5927\u5229\uff0c\u963f\u67cf\u897f\u666e\u7684\u4f7f\u7528\u53d7AIFA <\/strong>\u7b2c98<\/strong>\u53f7\u6587\u4ef6\uff08Nota 98<\/strong>\uff09\u7684<\/strong>\u76d1\u7ba1\uff0c\u8be5\u6587\u4ef6\u660e\u786e\u4e86\u6297VEGF<\/strong>\u836f\u7269\u73bb\u7483\u4f53\u5185\u6ce8\u5c04\u7684\u62a5\u9500\u6761\u4ef6\u3002 \n<\/strong>\u8be5\u6587\u4ef6\u89c4\u5b9a\u4e86\u53ef\u62a5\u9500\u7684\u75be\u75c5\u8303\u56f4\uff08nAMD<\/strong>\u3001DME<\/strong>\u3001<\/strong>\u89c6\u7f51\u819c\u9759\u8109\u963b\u585e\u53ca\u65e9\u4ea7\u513f\u89c6\u7f51\u819c\u75c5\u53d8\uff09\uff0c\u5e76\u8981\u6c42\u6240\u6709\u5904\u65b9\u548c\u7ed9\u836f\u5747\u987b\u5728\u7ecf\u6388\u6743\u7684\u773c\u79d1\u4e2d\u5fc3<\/strong>\u8fdb\u884c\u3002<\/p>\n\n

\u6240\u6709\u6cbb\u7597\u5747\u9700\u5f55\u5165 AIFA \u7684\u6570\u5b57\u5316\u767b\u8bb0\u7cfb\u7edf\uff0c\u4ee5\u786e\u4fdd\u6cbb<\/strong>\u7597\u9002\u5b9c\u6027\u3001\u5b89\u5168\u6027<\/strong>\uff0c\u5e76\u79ef\u7d2f\u771f\u5b9e\u4e16\u754c\uff08real-world\uff09\u6570\u636e\uff0c\u4e3a\u5168\u56fd\u6027\u6cbb\u7597\u8bc4\u4f30\u63d0\u4f9b\u652f\u6301\u3002<\/p>\n\n

\n\n

\u6cbb<\/strong>\u7597\u6548\u679c\u4e0e\u672a\u6765\u5c55\u671b<\/strong><\/h2>\n\n

\u4e34\u5e8a\u7814\u7a76\u4e0e\u771f\u5b9e\u4e16\u754c\u8bc1\u636e\u5747\u8868\u660e\uff0c\u963f\u67cf\u897f\u666e\u5728\u957f\u671f\u6cbb\u7597\u4e2d\u5c55\u73b0\u51fa\u7597\u6548\u4e0e\u5b89\u5168\u6027\u7684\u6700\u4f73\u5e73\u8861<\/strong>\u3002\u51ed\u501f\u5ef6\u957f\u6cbb\u7597\u95f4\u9694\u7684\u80fd\u529b\u53ca\u5728\u4e3b\u8981\u89c6\u7f51\u819c\u8840\u7ba1\u75be\u75c5\u4e2d\u7684\u786e\u5207\u7597\u6548\uff0c\u5b83\u5df2\u6210\u4e3a\u5f53\u4eca\u773c\u79d1<\/strong>\u9886\u57df\u6700\u5148\u8fdb\u4e14\u53ef\u6301\u7eed\u7684\u7597\u6cd5\u4e4b\u4e00<\/strong>\u3002<\/p>\n\n

\u914d\u65b9\u7684\u6f14\u53d8\u548c\u89c2\u5bdf\u6570\u636e\u7684\u65e5\u76ca\u589e\u591a\u6709\u671b\u5728\u4f9d\u4ece\u6027\u3001\u4e34\u5e8a\u7ba1\u7406\u548c\u533b\u7597\u8d44\u6e90\u4f18\u5316\u65b9\u9762\u53d6\u5f97\u8fdb\u4e00\u6b65\u7684\u6539\u5584\u3002<\/p>\n\n

\n\n

\u8d85\u8d8a<\/strong>\u89c6\u7f51\u819c\u75be\u75c5\uff1a\u7cbe\u51c6\u6cbb\u7597\u7684\u5178\u8303<\/strong><\/h2>\n\n

\u963f\u67cf\u897f\u666e\u540c\u65f6\u4e5f\u662f\u751f\u7269\u6280\u672f\u7814\u7a76\u6210\u679c\u7684\u5178\u8303\uff0c\u5c55\u793a\u4e86\u5982\u4f55\u901a\u8fc7\u9776\u5411\u673a\u5236<\/strong>\u5f00\u53d1\u51fa\u9ad8<\/strong>\u9009\u62e9\u6027\u548c\u591a\u9002\u5e94\u75c7\u7684\u6cbb\u7597\u65b9\u6848<\/strong>\u3002\u5176\u5bf9\u75c5\u7406\u6027\u8840\u7ba1\u751f\u6210\u7684\u9009\u62e9\u6027\u6291\u5236\u673a\u5236\u5177\u6709\u5e7f\u6cdb\u7684\u533b\u5b66\u610f\u4e49\uff0c\u8fdb\u4e00\u6b65\u8bc1\u660e\u4e86\u8be5\u5206\u5b50\u7684\u79d1\u5b66\u548c\u4e34\u5e8a\u4ef7\u503c\u3002<\/p>\n\n

\n\n

\u7ed3\u8bba<\/strong><\/h2>\n\n

\u963f\u67cf\u897f\u666e\u6539\u53d8\u4e86\u89c6\u7f51\u819c\u75be\u75c5\u7684\u6cbb\u7597\u683c\u5c40\uff0c\u63d0\u4f9b\u4e86\u4e00\u79cd\u5b89\u5168\u3001\u9ad8\u6548\u4e14\u53ef\u6301<\/strong>\u7eed\u7684\u7597\u6cd5<\/strong>\u3002\u5176\u5f71\u54cd\u4e0d\u4ec5\u9650\u4e8e\u4e34\u5e8a\u7597\u6548\uff1a\u5b83\u51cf\u8f7b\u4e86\u60a3\u8005\u53ca\u533b\u7597\u7cfb\u7edf\u7684\u8d1f\u62c5\uff0c\u6709\u52a9\u4e8e\u4fdd\u6301\u89c6\u529b\uff0c\u4ece\u800c\u7ef4\u62a4\u60a3\u8005\u7684\u72ec\u7acb\u6027\u4e0e\u751f\u6d3b\u8d28\u91cf\u3002\u5728\u8ffd\u6c42\u521b\u65b0\u4e0e\u53ef\u53ca\u6027\u5e73\u8861\u7684\u533b\u7597\u73af\u5883\u4e2d\uff0c\u963f\u67cf\u897f\u666e\u5df2\u6210\u4e3a\u73b0\u4ee3\u773c\u79d1\u533b\u5b66\u7684\u53c2\u8003\u5178\u8303\u3002<\/p>\n\n

\u5982\u9700\u4e86\u89e3\u6709\u5173\u963f\u67cf\u897f\u666e\u539f\u6599<\/strong>\u836f\uff08API<\/strong>\uff09\u6216\u5236<\/strong>\u5242\u4ea7\u54c1\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8054\u7cfb Old Pharma <\/strong>\u56e2\u961f\uff0c\u6211\u4eec\u5c06\u5f88\u4e50\u610f\u4e3a\u60a8\u63d0\u4f9b\u6280\u672f\u548c\u79d1\u5b66\u652f\u6301\u3002<\/strong><\/p>\n\n

\u53c2\u8003\u6587\u732e\u4e0e\u5ef6\u4f38<\/strong>\u9605\u8bfb<\/strong><\/h2>\n\n
    \n
  1. \u610f\u5927\u5229\u836f\u54c1\u7ba1\u7406\u5c40\uff08AIFA\uff09\uff0c\u7b2c<\/strong>98<\/strong>\u53f7\u6587\u4ef6 \u2013 <\/strong>\u6297VEGF<\/strong>\u73bb\u7483\u4f53\u6ce8\u5c04<\/strong>\u836f\u7269<\/strong>\uff1ahttps:\/\/www.aifa.gov.it\/nota-98<\/a><\/li>\n\n\n\n
  2. \u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\uff0c\u963f\u67cf\u897f\u666e<\/strong>\u836f\u54c1\u8bf4\u660e\u4e66\uff08EPAR<\/strong>\uff09<\/strong>\uff1ahttps:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/eylea<\/a><\/li>\n\n\n\n
  3. PubMed Central\uff0c\u963f\u67cf\u897f\u666e\u7597\u6548\u4e0e\u5b89\u5168\u6027\u7efc\u8ff0<\/strong>\uff1a https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12184776\/<\/a><\/li>\n\n\n\n
  4. Gazzetta Ufficiale, Pubblicazione Nota AIFA 98 (2024): https:\/\/www.gazzettaufficiale.it\/eli\/id\/2024\/02\/02\/24A00559\/sg<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

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